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自六十年代以来,国外许多学者从免疫学角度对肝炎的发生机制进行了大量研究,积累了丰富的实验和临床资料,从而使人们对肝炎有了新的认识。本文就有关这方面的文献综述介绍如下: 一、肝炎患者的自身抗体肝炎病人的体内有许多自身抗体,如抗肝细胞膜抗体、抗核抗体、抗线粒体抗体、抗平滑肌抗体等。这些抗体对肝细胞膜和相应的组织均有一定程度的损伤作用。其中,抗肝细胞膜抗体对肝炎的致病意义可能最大。
Since the 1960s, many foreign scholars have done a great deal of research on the pathogenesis of hepatitis from the perspective of immunology and have accumulated rich experimental and clinical data, so that people have a new understanding of hepatitis. This article on the literature review described in this regard are as follows: First, hepatitis patients with autoantibodies Hepatitis patients have many autoantibodies in vivo, such as anti-hepatocyte membrane antibodies, anti-nuclear antibodies, anti-mitochondrial antibodies, anti-smooth muscle antibodies. These antibodies on the liver cell membrane and the corresponding tissue have a certain degree of damage. Among them, the anti-hepatocyte membrane antibodies on the pathogenic significance of hepatitis may be the largest.