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孢子丝菌病(sporotrichosis)是一种真菌病。口腔一般的真菌病多为白色念珠菌感染,孢子丝菌病国内未有报告,本院收治一例报告如下: 女,27岁,病检号80060。数年前于外院在唇部切除过一个“粉瘤”;十个月前又在上唇基底部长有一硬块,活动,逐渐增大,无痛,中等硬度。临床检查:唇侧基底部摸到约弹珠大的肿物,活动,无压痛,界线不大清楚,粘膜有手术疤痕。手术所见:局麻下切开钝性分离肿物,部分包膜有粘连,肿物完整取出。临床疑为上颌骨粉瘤或上颌骨纤维瘤而送病理检查。肉眼标本见上唇根部软组织大小为1.5×1.3×0.6cm,灰红色粗糙,未见明显包膜,切面灰白色中有坏死灶。显微镜检查:可见上皮样细胞增生,大量淋巴细胞、浆细胞或单核细胞浸润,偶见嗜酸性细胞浸润的肉芽组织,肉芽肿中央大片坏死,于坏死灶中找到圆形、卵圆形的孢子,HE染色为嗜碱性,和针
Sporotrichosis is a fungal disease. Oral common fungal disease are mostly Candida albicans infection, sporotrichosis is not reported in our country, our hospital admitted a case report as follows: Female, 27 years old, disease inspection number 80060. A few years ago in the outer hospital in the lip resection had a “powder tumor”; Ten months ago in the upper lip base minister has a lump, activity, gradually increased, painless, medium hardness. Clinical examination: labial base touched about marbles large tumor, activity, no tenderness, the line is not clear, the mucosa with surgical scars. Surgical findings: local anesthesia incision under the blunt dissection of the tumor, part of the capsule adhesion, complete removal of the tumor. Clinical suspected maxillary bone tumor or maxillary fibroids sent pathological examination. The naked eye specimens see the upper lip root soft tissue size of 1.5 × 1.3 × 0.6cm, gray-red rough, no obvious envelope, cut off the gray necrotic lesions. Microscopic examination revealed epithelial-like cell proliferation, massive infiltration of lymphocytes, plasma cells or monocytes, occasionally eosinophilic infiltration of granulation tissue, central granulomatous necrosis, and finding of round, oval-shaped spores in necrotic foci , HE stained basophilic, and needles