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T小淋巴细胞性淋巴瘤/白血病在国外文献中常常放在T细胞慢性淋巴细胞性白血病(T—CLL)中.免疫学上可进一步分为辅助性(CD4+CLL)或抑制性(CD8+CLL)两种类型.一般认为CD8+CLL是一种大颗粒性淋巴细胞肿瘤性增生,瘤细胞具有规则圆形核,胞浆丰富,内含许多嗜天青颗粒;而CD4+CLL瘤细胞核形不规则,胞浆内无嗜天青颗粒.但是我们发现3例具有抑制性表型的T/小淋巴细胞性肿瘤,其临床表现以及形态学特征明显不同于文献所报告的CD8+CLL.
Small lymphocytic lymphoma / leukemia is frequently described in foreign literature as T-cell chronic lymphocytic leukemia (T-CLL), which can be further subdivided into helper (CD4 + CLL) or inhibitory (CD8 + CLL) are two types of CD8 + CLL is generally believed that a large granular lymphocytic neoplasia, tumor cells with a regular round nucleus, abundant cytoplasm, containing many azurophilic granules; and CD4 + CLL tumor nucleus Irregular, cytoplasm without aztreosone, but we found that 3 cases of T / small lymphoid tumors with inhibitory phenotype, the clinical manifestations and morphological characteristics were significantly different from the literature reported CD8 + CLL.