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用125IUdR释放法分别测定了38例急性病毒性心肌炎患者及58例正常人外周血自然杀伤细胞(NK)活性,结果表明:急性病毒性心肌炎患者的NK细胞活性(21+6.8%)明显低于正常人(35.2+10.4%)(p<0.01)。并发现NK细胞活性与预后有关。NK细胞活性愈低,预后愈差。提示NK细胞活性可作为诊断急性病毒性心肌炎及判断其疗效和预后的一项免疫监测指标。
The NK cell activity in peripheral blood of 38 patients with acute viral myocarditis and 58 healthy controls were measured by 125IUdR release assay. The results showed that NK cell activity (21 + 6.8%) was significantly lower in patients with acute viral myocarditis Normal (35.2 + 10.4%) (p <0.01). And found that NK cell activity and prognosis. The lower the NK cell activity, the poorer the prognosis. Suggesting that NK cell activity can be used as an indicator of diagnosis of acute viral myocarditis and to determine its efficacy and prognosis of an immune monitoring.