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为了探讨弦线时间常数（τｃｈ）和 Ｆ Ｖ 曲线形状在检查吸烟者小气道功能中的意义，作者对１１６ 例被动和轻、重度主动吸烟者进行了常规肺通气功能τｃｈ 和 Ｆ Ｖ 曲线形状检查。τｃｈ 用 Ｋｎｕｄｓｏｎ 方法计算，τｃｈ ＝ Ｖ／· Ｖ 。结果：凸型 Ｆ Ｖ 曲线分布随吸烟程度而上升，重度吸烟组和凸型 Ｆ Ｖ 曲线的τｃｈ ５０ 均延长到预计值的 １３０％ ，轻度吸烟组τｃｈ５０ 延长到１２０％ 。反映吸烟者小气道功能已有不同程度障碍，提示τｃｈ５０ 是检查小气道功能敏感而特异的指标。与前测 Ｃ Ｏ Ｐ Ｄ患者比较，其τｃｈ７５ 、τｃｈ５０ 、τｃｈ２５ 均随病情加重而延长，反映大小气道都遭累及。提示τｃｈ ５０ 对小气道功能的特异性以及 τｃｈ 在 Ｃ Ｏ Ｐ Ｄ 患者随病情加重而延长的规律性，对病情诊断具有临床意义，值得推广应用。
In order to explore the chord line time constant (τch) and F-V curve shape in the examination of smoker small airway function, the author of 116 cases of passive and light and severe active smokers were routine pulmonary ventilation function τch and F V curve Shape check. τch is calculated using the Knudson method, τch = V / · V. Results: The distribution of convex FV curve increased with the degree of smoking. The τch 50 values of both the heavy smoking group and the convex FV curve were prolonged to 130% of the expected value, while the τch50 of mild smoking group was prolonged to 120%. Small smokers reflect the airway function has varying degrees of obstacles, suggesting that τch50 is a small and sensitive airway function-specific indicators. Compared with the pre-test C O P D patients, the τch75, τch50 and τch25 were prolonged with the exacerbations, reflecting the involvement of the size airway. It is suggested that the specificity of τch 50 for the function of small airways and the regularity of τch prolonging with COPD in patients with COPD are of clinical significance for the diagnosis of the disease and should be popularized and applied.