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近年颇多报告卡马西平可治疗精神症状,但当该药血浓过高时则会使精神疵状恶化。福岛报告一例癫痫患者在使用该药治疗时,虽血浓正常,却出现明显记忆障碍;患者男,22岁,饭店炊事员。诊断外伤性癫痫。给予卡马西平150mg/日,三周后测血浓为3.8ug/ml,第四周时药量增至200 mg/日;不久诉嗜睡,至第七周诉遗忘严重,所学烹调技术不能追忆,差错百出,深感力不从心,极为苦恼。检查时:意识清,注意与定向力
In recent years, many reports of carbamazepine can be psychiatric symptoms, but when the drug is too high, it will make mental defects worse. Fukushima reported a case of epileptic patients in the use of the drug treatment, although the blood is normal, but there was a clear memory impairment; patient male, 22 years old, the hotel cook. Diagnosis of traumatic epilepsy. Given carbamazepine 150mg / day, three weeks after the test blood concentration was 3.8ug / ml, the fourth week when the dose increased to 200 mg / day; soon complained of lethargy, to the seventh week vomit forgotten serious, cooking techniques can not learn Remembrance, mistakes, deeply feel powerless, extremely distressed. Inspection: clear consciousness, attention and orientation