自Iversen(1951年)和Vernier(1958年)分别首先报告对215例成人和130例小儿开展经皮肤肾穿刺活检后,随着电镜和免疫荧光技术等相继广泛应用,肾活检技术在国外已日益成为人们对肾脏病免疫发病机理研究、病理分型、诊断、治疗和判断预后等必不可少的手段。到1971年为止,仅美国就已进行2万例以 Since Iversen (1951) and Vernier (1958) first report on percutaneous transcutaneous renal biopsy of 215 adults and 130 children, with the widespread application of electron microscopy and immunofluorescence techniques, renal biopsy techniques have been increasingly developed abroad Become people’s Nephrotic immune pathogenesis research, pathological type, diagnosis, treatment and prognosis and other essential means. As of 1971, only 20,000 cases have been taken in the United States alone