抵抗素(resistin)是近年来发现的一个新的脂肪细胞因子,它能对抗胰岛素,减弱胰岛素刺激细胞摄取葡萄糖的作用,降低糖耐量,促进脂肪细胞的增生,在肥胖、胰岛素抵抗和2型糖尿病之间可能起较为重要的作用。随着进一步研究发现,抵抗素能调节炎症反应而非胰岛素敏感性,它能促进炎症发生,与炎症的相关性更为密切[1]。因此,抵抗素复杂的生理功能受 Resistin is a new adipocytokine discovered in recent years. It can antagonize insulin, weaken the effect of insulin in stimulating cellular glucose uptake, decrease glucose tolerance, and promote the proliferation of adipocytes. In the aspects of obesity, insulin resistance and type 2 diabetes mellitus May play a more important role. As further studies have shown that resistin can regulate the inflammatory response rather than insulin sensitivity, it can promote the occurrence of inflammation, and the inflammation is more closely related [1]. Therefore, resistin complex physiological function by