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为了使对皮质激素疗法不敏感的支气管哮喘患者缓解其病情,则需加大剂量,强的松龙的日需要量往往不少于20mg,因此患者易产生免疫抑制,并可引起肾上腺皮质萎缩、糖尿病和骨质疏松等。趋向淋巴管皮质激素疗法,能使激素持续保持适宜的浓度,减少维持疗效的剂量,从而减少并发症和副作用.作者观察皮质激素依赖性支气管哮喘58例,年龄16~67岁,对皮质激素敏感者23例,不敏感者35例.病人分两组,基本组26(女14,男12)例,采用趋向淋巴管的皮质激素疗法。先用袖式血压带固定于大腿上,充气压力达40mmHg 维持3小时,使下肢组织液向淋巴管流动,再用无针头注射器《БИ-3》经小腿后中部皮肤注入芬兰产甲强龙 Methipred。根据病情每1~2天注入1次,每次20~40mg,共5~7次。对照组32(女17,男15)例,年龄和病情与基本组相似,且每日口服、肌注或静注皮质激素。两组都静注氨茶碱,用祛痰剂和多种维生素;肾上腺区作感应电热疗
In order to make corticosteroid therapy is not sensitive to patients with bronchial asthma to alleviate their condition, you need to increase the dose, prednisolone daily demand is often not less than 20mg, so patients prone to immune suppression, and can cause adrenal atrophy, Diabetes and osteoporosis. Tendency to lymphatic cortical hormone therapy, hormone can continue to maintain the appropriate concentration, reduce the dose to maintain efficacy, thereby reducing complications and side effects.We observed 58 patients with corticosteroid-dependent bronchial asthma, aged 16 to 67 years old, sensitive to corticosteroids 23 cases, 35 cases of insensitivity.The patients were divided into two groups, the basic group 26 (female 14, male 12) cases, the trend of lymphatic cortical hormone therapy. The first use of blood pressure cuff fixed to the thigh, inflatable pressure 40mmHg for 3 hours, the lower extremity tissue fluid flow to the lymphatic vessels, and then needleless syringe “БИ-3” through the calf after the middle of the skin into Finland Methylred methylprednisolone. According to the disease every 1 to 2 days into 1, each 20 ~ 40mg, a total of 5 to 7 times. Control group 32 (female 17, male 15) cases, age and condition similar to the basic group, and daily oral, intramuscular or intravenous corticosteroids. Both groups were intravenous aminophylline, with expectorants and a variety of vitamins; adrenal area for induction of electrothermal therapy