In this study on the biological activity of selenium-enriched mussel extract. rdts were randomly separated into three weight groups fed a basal selenium-deficient diet. diet supplemented by selenium from sodium selenite. and selenium enriched mussel extract. aspectively. Body weights of the rats were determined and metabolic experiment Was conducted after 4 weeks. The rats were killed after 8 weeks. Glutathione peroxidase activity and selenium content in liver and blood were determined. The results showed that selenium in mussel extract could be better absorbed by the rats and effectively promote their growth.There were no significant differences in glutathione peroxidase activity between the rats fed mussel extract or sodium selenite. Compared with sodium selenite group. the selenium content in blood and liver was significantly higher in the rats fed mussel extract. In this study on the biological activity of selenium-enriched mussel extract. Rdts were randomly separated into three weight groups fed a basal selenium-deficient diet. Diet supplemented by selenium from sodium selenite. And selenium enriched mussel extract. Aslyly. Body weights of the The rats were determined and the serum content was determined in liver and blood were determined. The results showed that selenium in mussel extract could be better absorbed by the rats and effectively promote their growth. There were no significant differences in glutathione peroxidase activity between the rats fed mussel extract or sodium selenite. Compared with sodium selenite group. the selenium content in blood and liver was significantly higher in the rats fed mussel extract.