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因胸痛接受选择性冠状动脉造影７８例，其中有冠状动脉病变者５ｌ例，冠脉造影正常者２７例。测定所有病例的胆固醇、甘油三脂、高密度脂蛋白及其亚组分、载脂蛋白Ａ１和Ｂ１００分析冠脉病变程度与血清脂类和载脂蛋白的相关性，比较后二者对冠心病的辨别力，结果表明：单项指标对冠心病的辨别力以载脂蛋白Ａ１为佳；血脂分组比值以非高密度脂蛋白与高密度脂蛋白之比为优。提示测定载脂蛋白Ａ１和Ｂ１００以及非高密度脂蛋白与高密度脂蛋白之比对于临床预测冠脉病变有实用价值。
Selective coronary angiography was performed in 78 patients for chest pain, including 5l coronary artery lesions and 27 normal coronary angiography. The cholesterol, triglyceride, high-density lipoprotein and its sub-components in all cases were determined. The correlation between the degree of coronary artery lesions and serum lipids and apolipoproteins was analyzed by apolipoprotein A1 and B100. The results showed that the discriminating ability of single index on coronary heart disease was better with apolipoprotein A1; the ratio of blood lipid group was better than the ratio of non-high density lipoprotein to high density lipoprotein. Prompt determination of apolipoprotein A1 and B100 and non-high-density lipoprotein and high-density lipoprotein ratio for the clinical prediction of coronary artery disease has practical value.