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目的 探讨羊膜移植术（ＡＭＴ）在治疗大泡性角膜病变（ＢＫ）中的应用价值。方法 选择伴有明显眼痛且视功能较差的 ＢＫ１１例（１１只眼）。其中无晶状体 ＢＫ ５例，人工晶状体 ＢＫ ４例，其他原因所致 ＢＫ ２例，采用 ＡＭＴ进行治疗。术后裂隙灯及荧光素染色检查，平均随访１６周。结果．１１例中９例术后当天眼痛消失，２例３天后消失。７例出现暂时性的角膜上皮缺损，３周内全部愈合，羊膜植片完整８例，不完全融解３例。除１例出现周边角膜上皮性水泡外，均未发现ＢＫ复发。全部病人无新生血管及翼状胬肉发生。结论 ＡＭＴ可有效地改善基质层微环境，重建角膜表面，减轻炎症反应和疼痛，防止ＢＫ复发，是治疗ＢＫ可供选择的有效方法。
Objective To investigate the value of amniotic membrane transplantation (AMT) in the treatment of bullous keratopathy (BK). Methods BK11 patients (11 eyes) with obvious eye pain and poor visual function were selected. Including aphakia BK 5 cases, intraocular lens BK 4 cases, other causes of BK 2 cases, the use of AMT for treatment. Postoperative slit lamp and fluorescein staining were followed up for an average of 16 weeks. result. In 11 cases, 9 cases of eye pain disappeared on the day after operation, and 2 cases disappeared after 3 days. 7 cases of temporary corneal epithelial defects, all within 3 weeks of healing, amniotic membrane integrity in 8 cases, incomplete melting in 3 cases. No recurrence of BK was found except for one case of peripheral corneal epithelial blister. All patients without neovascularization and pterygium occurred. Conclusion AMT can effectively improve the microenvironment of the stroma, reconstruct the corneal surface, reduce inflammation and pain, and prevent the recurrence of BK. It is an effective and effective method for the treatment of BK.