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一、前言众所周知,孕妇一旦患有风疹,其胎儿的白内障、心脏病、听力减退、智力发育迟缓等先天性异常的发病率就将增高。在日本为了预防这种先天性风疹综合征的发生,从1977年秋起,以中学女生为对象,进行了风疹疫苗的定期接种。可是,在疫苗接种组包括实际并未接受疫苗接种者在内,有4.0～8.2%的抗体阴性。在没有接受定期接种风疹疫苗组的妇女中有近30%的抗体阴性。1987年春开始的全国性风疹大流行,给这些风疹抗体阴性的妊娠妇女带来很大的冲击。风疹抗体阴性的成年妇女,为了防止先天性风疹综合征的发生,积极地要求在未妊娠时接受疫苗接
First, the preamble As we all know, once suffering from rubella pregnant women, their fetus cataracts, heart disease, hearing loss, mental retardation and other congenital anomalies will increase the incidence. In order to prevent the occurrence of this congenital rubella syndrome in Japan, from the fall of 1977, regular immunization of the rubella vaccine was conducted for girls in secondary schools. However, there were 4.0 to 8.2% antibody negative in the vaccination group, including those who did not actually receive the vaccine. Nearly 30% of women who did not receive regular rubella vaccine were negative. The national rubella pandemic, which started in the spring of 1987, has had a huge impact on these rubella-negative pregnant women. Rubella antibody negative adult women, in order to prevent the occurrence of congenital rubella syndrome, and actively require vaccination in the absence of pregnancy