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本文报道用ATG(抗胸腺细胞球蛋白)和ALG(抗淋巴细胞球蛋白)治疗2例重症再生障碍贫血,效果显著。例1,男性23岁,入院时血液检查:红细胞171×10~4/μl、血红蛋白(Hb)6.5g/dL、血小板2.1×10~4/μL,各类血细胞严重减少。应用大量强的松龙(MPSL)治疗2个疗程无效。给予ATG(20mg/kg/日)静点,总量5g,10周后取得良好效果,骨髓穿刺检查有核细胞由1.5×10~4/μL 堵至11.5×10~4/μL。一年后Hb 增至15.7g/dL、颗粒细胞1580/μL、血小板9.2×10~4/μL,ATG 的治疗效果显著。
This article reports the use of ATG (anti-thymocyte globulin) and ALG (anti-lymphocyte globulin) treatment of 2 cases of severe aplastic anemia, the effect is significant. Example 1 Male 23 years old, blood examination on admission: red blood cells 171 × 10 ~ 4 / μl, hemoglobin (Hb) 6.5g / dL, platelets 2.1 × 10 ~ 4 / μL, all kinds of serious decline in blood cells. Application of a large number of prednisolone (MPSL) treatment 2 courses invalid. A total of 5 g ATG (20 mg / kg / day) was given intravenously to achieve a good effect after 10 weeks. The number of nucleated cells in the bone marrow aspirate was blocked from 1.5 × 10 4 / μL to 11.5 × 10 4 / μL. One year later Hb increased to 15.7g / dL, granulosa cells 1580 / μL, platelet 9.2 × 10 ~ 4 / μL, ATG treatment effect is significant.