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【目的】探讨新生儿窒息后患儿血清心肌肌钙蛋白I水平及其临床意义。【方法】采用全自动化学免疫系统检测34例窒息新生儿的血清心肌肌钙蛋白I(cardiactroponinI,cTnI),并与10例对照组新生儿进行对照比较。【结果】窒息新生儿血清cTnI浓度明显升高,与对照组比较差异有显著性(P<0.05),重度窒息组新生儿血清cTnI浓度与轻度窒息组比较明显升高(P<0.05)。【结论】新生儿cTnI浓度与窒息程度成正比关系,对于预测新生儿窒息患儿心肌损害有重要意义。
【Objective】 To investigate the serum level of cardiac troponin I in neonates with asphyxia and its clinical significance. 【Methods】 Serum cardiac troponin I (cTnI) was detected in 34 neonates with asphyxia by automatic chemical immunology system and compared with 10 neonates in control group. 【Results】 Serum cTnI levels in neonates with asphyxia were significantly higher than those in control group (P <0.05). Serum cTnI levels in neonates with severe asphyxia group were significantly higher than those in mild asphyxia group (P <0.05). 【Conclusion】 The neonatal cTnI concentration is directly proportional to the degree of asphyxia, which is of great significance for the prediction of myocardial damage in neonates with asphyxia.