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用马来丝虫成虫冰冻切片抗原作间接荧光抗体试验(IPAT),以1:20稀释样本检测丝虫抗体的阳性符合率为97.50%,假阳性率为2.44%。在282名流动人口中抗体阳性率为16.31%(46/282)。自1987年以来我省抽样进行血清流行病学调查,人群丝虫抗体水平逐年下降,1992年对21个县市10798人份血样检测,显示基本消灭丝虫病8~11年后人群抗体平均阳性率为3.18%,GMRT为25.59,已接近非流行区健康人水平(2.44%).结果表明丝虫病流行区经海群生防治后的效果是稳定的,IFAT用于现场监测能反映丝虫病流行的实际情况。
Indirect fluorescent antibody test (IPAT) was performed on the frozen sections of adult Malayan worms, and the positive coincidence rate was 97.50% and the false positive rate was 2.44%. The positive rate of antibody in 282 floating population was 16.31% (46/282). Serological epidemiological survey was carried out in our province since 1987, the population of filarial and attenuated antibody levels declines year by year. In 1992, blood samples of 10798 people from 21 counties and cities were detected, showing that the average antibody was positive after 8 to 11 years of basic elimination of filariasis The rate was 3.18% and the GMRT was 25.59, which was close to that of non-endemic area (2.44%). The results showed that the prevalence of endemic filariasis in the endemic areas was stable after the control of sea fauna, and IFAT was used in field monitoring to reflect the prevalence of filariasis.