肾移植后高血压症发病机理复杂,多数病人为多种因素所致。免疫抑制剂起决定性作用,特别是Ciclosporin和皮质激素,在用Ciclosporin前只有40％～50％病例发生高血压。一般认为免疫抑制剂致移植后高血压有不同的机制,肾素血管紧张素系统常受到抑制。在应用Ciclosporin几周内形成高血压,特征是无夜间血压下降,少见的是并发血栓性微血管病。新的免疫抑制剂(FK506)可能具有相似的肾 The pathogenesis of hypertension after renal transplantation is complex, most patients due to a variety of factors. Immunosuppressive agents play a decisive role, especially Ciclosporin and corticosteroids, and only 40% to 50% of cases precede Ciclosporin. Generally believed that immunosuppressive agents have different mechanisms of post-transplant hypertension, the renin-angiotensin system is often inhibited. Hypertension develops within weeks of application of Ciclosporin and is characterized by no decrease in nocturnal blood pressure, with rare thrombotic microvascular disease. The new immunosuppressant (FK506) may have a similar kidney