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目的：了解Ｌ型细菌的临床分离情况、感染特点及耐药性。方法：采用高渗培养基对泌尿系统感染患者的尿标本进行增菌；用ＡＰＩ细菌鉴定系统进行菌株种属分析；药物敏感试验采用微量肉汤稀释法。结果：Ｌ型细菌的临床分离株以大肠杆菌为主（４０７％），其次是肠球菌属（１２６％）；临床感染患者主要来自普通门诊，头孢唑林、环丙沙星、诺氟沙星均有较高的耐药率。结论：Ｌ型细菌在泌尿系统感染中占有重要的地位。传统的喹诺酮类抗生素呈现较高的抗药性，临床治疗选择抗生素时应兼顾Ｌ型与细菌型。
Objective: To understand the clinical isolation of L-type bacteria, infection characteristics and drug resistance. Methods: Urine samples from patients with urinary tract infections were treated with hypertonic medium to enrich the urine specimens. The API bacterial identification system was used to analyze the species of the strains. The drug susceptibility test was performed using the broth microdilution method. Results: The main clinical isolates of L-type bacteria were Escherichia coli (407%), followed by Enterococcus (126%). The clinical infections were mainly from general clinic, cefazolin, ciprofloxacin, Norfloxacin has a higher resistance rate. Conclusion: L-type bacteria occupy an important position in the urinary tract infection. Traditional quinolone antibiotics show high resistance, clinical treatment of antibiotics should take into account the L-type and bacterial type.