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心房钠尿肽是一种具有强大的利钠、利尿、扩张血管作用的肽类激素,在胎盘和胎膜组织有丰富的表达,对维持妊娠期间正常的子宫胎盘循环和胎儿生长发育中起重要作用。目前研究发现,心房钠尿肽与妊娠期高血压疾病、胎儿生长受限、胎儿宫内窘迫等一些产科疾病关系密切。心房钠尿肽浓度变化对于这些疾病的诊断、治疗、及预后判断均起一定的作用。不久的将来,心房钠尿肽作为一种药物在临床的应用将越来越广。
Atrial natriuretic peptide is a potent sodium, diuretic and vasodilator peptide hormone that is abundantly expressed in the placenta and fetal membranes and plays an important role in maintaining normal uteroplacental circulation and fetal growth and development during pregnancy effect. The current study found that atrial natriuretic peptide and gestational hypertension, fetal growth restriction, fetal distress and some other obstetrical diseases are closely related. Atrial natriuretic peptide concentration changes for the diagnosis of these diseases, treatment, and prognosis play a role. The near future, atrial natriuretic peptide as a drug in clinical applications will be more and more widely.