Foley 等描叙过肝病患者的钝性棘慢波综合。这种波形后来被Bickford 和Butt 称为“三相波”。这种电活动尽管具有特性,却是非特异性的EEG 改变。它可见于各种代谢性及非代谢性脑病。值得提出的是三相波继发于用药后(例如服锂或氯苯氨丁酸),文献上曾报告,合用锂及左旋多巴中毒患者出现三相波,而在停用上述两种药物后,临床症状及三相波消失。本文首次报道左旋多巴诱发脑病,伴发周期 Foley et al described blunt spikes and slow waves in patients with liver disease. This waveform was later called “three-phase wave” by Bickford and Butt. This electrical activity, though characteristic, is a nonspecific EEG change. It can be found in a variety of metabolic and non-metabolic encephalopathy. It is worth mentioning that three-phase wave secondary to the medication (such as serving lithium or clofibrate), the literature has reported that patients with lithium and levodopa poisoning appear three-phase wave, and disable the two drugs After the clinical symptoms and three-phase wave disappeared. This article first reported levodopa induced encephalopathy, associated with the cycle