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目的:探讨低剂量米非司酮配伍卡前列甲酯栓终止哺乳期瘢痕子宫内早孕药物流产的疗效和安全性。方法:选择门诊行药物流产哺乳期瘢痕子宫(行子宫下段剖腹产术)内早孕妇女160例,第1、2天服用米非司酮胶囊后观察阴道出血时间、出血量,第3天应用卡孕栓后留院观察用药后流产效果、胚囊排出时间、排出情况、阴道出血量、出血时间及物药不良反应情况。结果:低剂量米非司酮配伍卡前列甲酯栓终止哺乳期瘢痕子宫内早孕完全流产144例(90%),不全流产12例(7.5%),药物流产失败4例。结论:低剂量米非司酮配伍卡前列甲酯栓终止哺乳期瘢痕子宫内早孕药物流产是有效和安全的。
Objective: To investigate the curative effect and safety of low dose mifepristone combined with carbamazepin suppository to terminate abortion of early pregnant women with uterine scar during lactation. Methods: One hundred and sixty-six pregnant women in the first trimester of scarring uterus (lower uterine segment caesarean section) were selected outpatient medical abortion. The vaginal bleeding time and bleeding volume were observed after taking mifepristone capsules on the first and second days. After the embolization, observe the effect of abortion, the time of embryo sac discharge, the discharge, the amount of vaginal bleeding, the bleeding time and adverse drug reactions. Results: 144 cases (90%) of complete abortion and incomplete abortion in 12 cases (7.5%) and 4 cases of abortion were terminated by low dose of mifepristone combined with carbamazepin suppository. Conclusion: It is effective and safe to use low dose of mifepristone combined with carbamazepin to stop the abortion of early pregnant women during early pregnancy.