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目的:探讨夫精宫腔内人工授精(IUI)时机与妊娠率间的关系。方法:回顾性分析122例不孕夫妇共行229周期,按IUI时机分尿黄体生成素(LH)阳性人绒促性腺素(HCG)注射后24 h行IUI、尿LH阴性HCG注射后36~38 h行IUI两组。依妊娠结局分析排卵前与排卵后IUI妊娠率的比较,HCG注射后24 h与36~38 h IUI排卵率的比较。结果:排卵后行IUI妊娠周期是20个周期(20/96,20.8%),排卵前IUI为10个周期(10/133,7.5%),差异有统计学意义(P<0.01)。HCG注射后24 h行IUI妊娠周期6个周期(6/39,15.4%),36~38 h后妊娠周期24周期(24/190,12.6%),两组差异无统计学意义(P>0.05)。结论:排卵后行IUI可以适当提高妊娠率。
Objective: To investigate the relationship between intrauterine insemination (IUI) timing and pregnancy rate in Fudan University. Methods: A total of 229 infertile couples were retrospectively analyzed. Twenty-four cycles of IUI were performed at 24 h after IUI injection of HCG, 38 h line IUI two groups. According to the outcome of pregnancy, the pregnancy rates of IUI before ovulation and after ovulation were compared, and the IUI ovulation rates between 24 h and 36 ~ 38 h after HCG injection were compared. Results: The IUI pregnancy cycle was 20 cycles (20/96, 20.8%) after ovulation and 10 cycles (10/133, 7.5%) before ovulation. The difference was statistically significant (P <0.01). The IUI pregnancy cycle was 6 cycles (6/39, 15.4%) at 24 h after HCG injection and 24 cycles (24/190, 12.6%) after 36-38 h. There was no significant difference between the two groups (P> 0.05 ). Conclusion: IUI after ovulation can raise the pregnancy rate properly.