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报告33例新生儿医院获得性细菌感染性肺炎,经气管插管采集气管深部分泌物44份,培养出62株细菌,所得细菌学资料显示链球菌为首要病原菌,其次为铜绿假单胞菌。一些条件致病菌也可引起医院获得性肺炎,药敏试验显示每株细菌对抗生素出现多重耐药性(耐5种以上抗生素),其中对青霉素、氨苄青霉素、新青霉素Ⅱ、羧苄青霉素、邻氯青霉素、先锋霉素V、头孢胺噻肟耐药率高达100%。提示医院获得性细菌感染性肺炎治疗困难。本组死亡3例,均为铜绿假单胞菌感染,因此铜绿假单胞菌感染是引起死亡的主要原因。
Reported 33 cases of neonatal hospital acquired bacterial pneumonia, endotracheal intubation collected tracheal secretions of 44, 62 strains of bacteria were cultured, the resulting bacteriological data showed that streptococcus is the primary pathogen, followed by Pseudomonas aeruginosa. Some opportunistic pathogens can also cause hospital-acquired pneumonia. Susceptibility testing shows that there is multiple resistance to antibiotics per bacterial strain (resistant to more than 5 antibiotics), of which penicillin, ampicillin, penicillin II, carbenicillin, Cloxacillin, cephalosporin V, cefotaxime resistance rates as high as 100%. Prompt hospital-acquired bacterial pneumonia treatment difficulties. The group died of 3 cases, both of Pseudomonas aeruginosa infection, so Pseudomonas aeruginosa infection is the main cause of death.