阿司匹林(ASA)使血小板环氧化酶乙酰化不可逆转,从而抑制血小板凝聚物——血栓质 A_2(TXA_2)的合成,对预防动静脉内血栓形成、卒中及一过性缺血性发作患者的死亡以及髋部外科手术后的栓塞有效,已证实具有抗血栓作用。既往经临床研究与动物实验证明,ASA 对雄性动物较雌性有显著抗血栓作用。 Aspirin (ASA) causes platelet cyclooxygenase acetylation to be irreversible, thereby inhibiting the synthesis of platelet aggregate-thromboxane A 2 (TXA 2) and preventing the development of arteriovenous thrombosis, stroke, and transient ischemic attacks Death and embolization after hip surgery have been shown to have antithrombotic effects. Previous clinical studies and animal experiments show that ASA has significantly antithrombotic effects on males compared to females.