对阿斯匹林和其它非甾体抗炎药物(NBAID)不耐受在哮喘患者中较为常见。本文报告在急性致命性严重哮喘发作中,阿斯匹林不耐受作为促发因素的发生情况。作者回顾1977～1986年间92例因哮喘急性发作进行机械通气患者的病历,发现13例(14%)既往有阿斯匹林或NSAID 诱发支气管痉挛的病史。其中7例(8%)哮喘严重发作是由NSAID 引起的.1例死亡。作者认为与其他作者报道结果不同,在严重的急性哮喘发作需用机械通气的患者中,NSAID 不耐受 Intolerance to aspirin and other non-steroidal anti-inflammatory drugs (NBAIDs) is more common in asthmatics. This article reports aspirin intolerance as a predisposing factor in acute, fatal asthma attacks. The authors reviewed the medical records of 92 patients with mechanical ventilation during the acute episode of asthma between 1977 and 1986 and found that 13 (14%) had previously had a history of aspirin or NSAID-induced bronchospasm. Serious asthma attacks were caused by NSAIDs in 7 (8%) of the patients, and 1 died. The authors concluded that unlike other authors who reported results, NSAID was intolerant in patients requiring mechanical ventilation for severe acute asthma attacks