大脑曲菌病较少见,其真正发病率不详。作者报告二例见于印度Tamil Nadu的大脑曲菌病,临床表现如颅内占位性病变,疑为颅内肿瘤,第一例为左额叶脓肿,以氢氧化钾直接涂片找到分枝、分隔菌丝,手术标本培养出杂色曲菌纯培养,切片中可见在巨细胞内外有直角形分枝、分隔的菌丝。患者经手术切除继以抗痉剂治疗,症状缓解了3年零9 Less common aspergillosis, the true incidence is unknown. The authors report two cases of cerebral aspergillosis found in Tamil Nadu, India, clinical manifestations such as intracranial space-occupying lesions, suspected intracranial tumors, the first case of left frontal abscess, potassium hydroxide direct smear to find branches, Separated mycelium, surgical specimens cultured pure cultures of Aspergillus versicolor, sliced ​​visible in the giant cells inside and outside the right-angle branches, separated mycelium. The patient was surgically removed and treated with anti-spasmodic agent for 3 years and 9 months