用毛细管气相色谱法分析,山鸡椒含有80种以上化学成分,其中所含的黄樟素有致癌作用。为了保障用药安全,本文对山鸡椒果实挥发油中的有效成分进行了研究,经化学分离、鉴定、药理筛选和临床验证,得到治疗冠心病的有效化学成分—柠檬醛。以柠檬醛作为治疗冠心病的新药,可避免山鸡椒挥发油中其它有害成分对人体的毒付作用,为寻找新药提供了信息。 Analysis by capillary gas chromatography, Sanjiaojiao contains more than 80 chemical constituents, and the contained safrole has a carcinogenic effect. In order to ensure the safety of medication, the active constituents in the essential oil of Shanjijiao fruit were studied in this paper. Chemical separation, identification, pharmacological screening and clinical validation were used to obtain the effective chemical constituent of citrinolide, citral. The use of citral as a new drug for the treatment of coronary heart disease can avoid the toxic effects of other harmful components in the volatile oil of Shanjiao pepper and provide information for the search for new drugs.