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目的探讨急性脑梗死患者血清尿酸水平与颈动脉粥样硬化程度的关系。方法对114例急性脑梗死患者进行血清尿酸水平的测定及颈动脉彩色超声检查,并按颈动脉彩超提示斑块情况分4组,比较不同程度颈动脉粥样硬化患者血清尿酸水平。结果组间性别、年龄、血脂、血糖比较无显著差异(P>0.05),随着颈动脉硬化程度的加重,血清尿酸水平呈上升趋势(P<0.05)。结论高尿酸血症对颈动脉粥样硬化的形成起重要作用,且与颈动脉粥样硬化程度呈正相关。
Objective To investigate the relationship between serum uric acid level and carotid atherosclerosis in patients with acute cerebral infarction. Methods 114 patients with acute cerebral infarction were measured serum uric acid levels and carotid color ultrasound, and according to carotid color Doppler ultrasound plaque were divided into 4 groups to compare the level of serum uric acid in patients with different degrees of carotid atherosclerosis. Results There were no significant differences in sex, age, blood lipid and blood glucose among the groups (P> 0.05). Serum uric acid levels showed an upward trend with the severity of carotid atherosclerosis (P <0.05). Conclusion Hyperuricemia plays an important role in the formation of carotid atherosclerosis and is positively correlated with the degree of carotid atherosclerosis.