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目的观察一氧化碳中毒性迟发性脑病的临床特点,CT及MRI检查,临床治疗效果。方法回顾研究本院16例一氧化碳中毒性迟发性脑病的患者,对疾病临床表现、影像学以及治疗效果进行分析。结果 9例表现为精神异常,5例表现为痴呆症状,1例表现为锥体外系症状,1例表现为锥体系症状和自主神经症状;CT和MRI均能发现异常,且MRI的敏感性高于CT;经高压氧及基础治疗后10例症状显著改善;3例部分改善,并遗留有轻微后遗症;3例改善不明显,仍然有脑病症状。结论一氧化碳中毒性迟发性脑病的临床表现不典型,但影像学表现较为典型,如能及早进行高压氧治疗,能明显缓解症状,降低致残率。
Objective To observe the clinical features of delayed carbon monoxide poisoning encephalopathy, CT and MRI examination, clinical treatment. Methods A retrospective study of 16 patients with delayed carbon monoxide poisoning encephalopathy in patients with clinical manifestations, imaging studies and treatment effects were analyzed. Results 9 cases showed mental abnormalities, 5 cases showed symptoms of dementia, 1 case showed extrapyramidal symptoms, 1 case showed pyramidal symptoms and autonomic symptoms; CT and MRI were found abnormal, and the MRI of high sensitivity In CT, the symptoms of 10 cases were significantly improved after hyperbaric oxygen and basal therapy, 3 cases were partially improved, slight sequelae left behind, 3 cases showed no obvious improvement and still had symptoms of encephalopathy. Conclusion The clinical manifestations of delayed carbon monoxide poisoning delayed encephalopathy is not typical, but the imaging findings are typical. If hyperbaric oxygen therapy can be carried out as soon as possible, the symptoms can be relieved and the morbidity reduced.