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本实验选用四氯化碳致大白鼠肝炎为模型,对具有退黄作用的水芹分别与瓜蒂、龙胆草、五味子和灵芝草四种传统中药配伍(生药比例均为1:1)制成50％的注射液,皮下注射,进行了退黄降酶疗效的实验和研究。结果表明,除水芹注射液5ml/kg,退黄显著(P<0.01),降酶不明显(P>0.05)和水芹五味子注射液10ml/kg,降酶显著(P<0.05)而退黄不明显(P>0.05)外,水芹的其它3种复方制剂(水芹瓜蒂2ml/kg、水芹龙胆草和水芹灵芝草各10ml/kg),均具有非常显著的退黄和降酶的疗效(P<0.01)。各组肝脏病理镜检结果与退黄降酶的疗效均相符。故初步认为水芹瓜蒂、水芹龙胆草,和水芹灵芝草注射液可能为治疗肝炎的新药。
In this experiment, carbon tetrachloride-induced rat hepatitis was used as a model, and the watercress with yellowing effect was combined with Guatea, Gentian, Schisandra, and Ganoderma lucidum, and the traditional Chinese medicines (the proportion of crude drug was 1:1) were used. Into 50% of the injection, subcutaneous injection, carried out the experimental study and study of the efficacy of jaundice. The results showed that with the addition of 5ml/kg watercress injection, the yellowing was significant (P<0.01), the drop of enzyme was not obvious (P>0.05) and the water drop of Schisandra chinensis injection was 10ml/kg, and the drop of enzyme was significant (P<0.05). The other three kinds of compound preparations of cress (2ml/kg of cress guatyre, 10g/kg each of watercress gentian and watercress ganoderma lucidum) have very significant yellowishness, but the yellow is not obvious (P>0.05). Efficacy and down-regulation (P<0.01). The results of pathological microscopy of liver in each group were consistent with the efficacy of jaundice and down-regulation. Therefore, it is initially believed that cress guati, cress gentian, and cress ganoderma lucidum injection may be new drugs for the treatment of hepatitis.