小儿复方新诺明片中每片含磺胺甲基异恶唑(以下简称SMZ)0.1g,其中 TMP 的含量测定是采用溶剂提取后的紫外分光光度法,操作复杂,结果偏低,且所用溶剂为有毒性的氯仿。本文对地方标准法作了部分改进,用硝酸银试液沉淀除去 SMZ,再用紫外分光光度法测定 TMP 含量,方法简便,快速,回收率高,结果准确,可供成品检验用。1 仪器、试药与试剂UV—2201型紫外分光光度计。;TMP 纯品:批号990455; Children’s compound cotrimoxazole tablets each containing sulfamethoxazole (hereinafter referred to as SMZ) 0.1g, of which TMP content is determined by solvent extraction UV spectrophotometry, the operation is complex, the result is low, and the solvent used For toxic chloroform. In this paper, the local standard method was partially improved. The SMZ was precipitated with silver nitrate solution, and the content of TMP was determined by UV spectrophotometry. The method was simple and rapid, the recovery rate was high, and the result was accurate. 1 instruments, reagents and reagents UV-2201 UV spectrophotometer. ; TMP pure product: batch number 990455;