低血糖期间肾上腺素能症状的感觉丧失,是Ⅰ型糖尿病(IDDM)发生严重低血糖的主要危险因素。这种缺陷一般发生在胰岛素治疗数年后,发生率约20％。其原因仍有争论,最初曾归因于自主神经病变,后来认为与肾上腺素能分泌缺乏有关。本文研究的目的在于证实,对低血糖症状感觉迟钝以至造成严重低血糖反复发作的糖尿病病人,是否存在对胰岛素引起低血糖的肾上腺素能分泌延迟。 14例IDDM分为两组。A组7例对低血糖的感觉丧失,并有严重、反复的低血糖发作;B组7例 The loss of adrenergic symptoms during hypoglycemia is a major risk factor for the development of severe hypoglycemia in type 1 diabetes mellitus (IDDM). This defect usually occurs in the insulin treatment after a few years, the incidence of about 20%. The reason there is still controversy, originally attributed to autonomic neuropathy, and later that the lack of adrenergic secretion. The purpose of this study was to determine whether there is a delay in the secretion of adrenergic insulin-induced hypoglycemia in diabetic patients who have hypoglycemic symptoms or have recurrent episodes of severe hypoglycaemia. 14 cases of IDDM divided into two groups. A group of 7 cases of loss of hypoglycemia, and severe, repeated episodes of hypoglycemia; B group of 7 patients