放射性碘可损伤甲状腺滤泡,这种损伤是不可逆的,故可造成甲状腺体积缩小。长期以来,放射性碘只用于治疗甲亢、甲状腺转移癌及甲状腺癌术后颈部残存的病灶。然而本文作者使用放射性碘治疗局部有压迫症状的多结节性非毒性甲状腺肿。 作者在过去的20年间,对15例巨块型多结节性非毒性甲状腺肿患者进行了观察。患者年龄62～86岁,平均67岁。甲状腺肿大不对称,有些病例伴有不同程度的胸骨后甲状腺肿。所有患者X线检查都有气管移位,60％病例有气管压迫症状。临床及生化 Radioactive iodine can damage thyroid follicles, this damage is irreversible, it can cause thyroid volume reduction. For a long time, radioactive iodine only for the treatment of hyperthyroidism, thyroid metastases and thyroid cancer residual neck lesions. However, the authors used radioactive iodine in the treatment of multi-nodular non-toxic goiter with localized compression symptoms. In the past 20 years, the authors observed 15 patients with massive tuberculous non-toxic goiter. Patients aged 62 to 86 years, mean 67 years. Goiter asymmetry, in some cases with varying degrees of post-sternum goiter. X-ray examination of all patients have tracheal displacement, 60% of cases have tracheal compression symptoms. Clinical and biochemical