目的了解马鞍山市既往有偿献血人员中戊型肝炎感染状况,为此类传染病防治提供依据。方法采集有偿献血人员及农村正常人群的血清,通过酶联免疫吸附试验检测血清中戊型肝炎病毒的IgG抗体。结果共检测标本992例,其中既往有偿献血人员492例,检测出抗HEV-IgG抗体阳性病例数126例,阳性率25.6%;正常农村人群500例,检测出40例阳性,阳性率8%。结论既往有偿献血人员戊型肝炎感染率显著高于一般人群,戊型肝炎经血传播的危险是一个客观存在和值得关注的问题。 Objective To understand the status of hepatitis E infection in previously paid blood donors in Ma’anshan City and provide the basis for the prevention and treatment of such infectious diseases. Methods Serum of paid blood donors and rural normal people were collected. Serum hepatitis E virus IgG antibody was detected by enzyme-linked immunosorbent assay (ELISA). Results A total of 992 specimens were detected, of whom 492 were previously paid blood donors, and 126 were positive for anti-HEV-IgG antibody. The positive rate was 25.6%. In the normal rural population, 500 were positive and 40 were positive. The positive rate was 8%. CONCLUSIONS: The prevalence of hepatitis E infection among paid blood donors was significantly higher than that of the general population. The risk of hepatitis E transmission through blood was an objective problem and a cause of concern.