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目的探讨以拮抗剂为主的五联疗法对慢性充血性心力衰竭(CHF)的治疗作用。方法 43例CHF 患者,分为两组,观察组23例,对照组20例,观察组用系统正规的五联疗法治疗1年,观察两组平均每次住院天数、平均再住院次数及病死率的变化。结果观察组每次住院天数为(12±8.6)d;再住院次数为(2.45±1.05)次;病死率为8%。对照组分别为(18±7.7)d、(3±1.26)次和病死率30%。两组间差异显著(分别为P<0.01、0.05及<0.05)。结论以拮抗剂为主的五联疗法对 CHF 治疗有明显的效果。
Objective To investigate the therapeutic effect of five-agent therapy based on antagonist on chronic congestive heart failure (CHF). Methods Forty-three CHF patients were divided into two groups: observation group (23 cases) and control group (20 cases). The observation group was treated with formal five-line therapy for one year. The average number of hospital stay, average number of rehospitalization and mortality The change. Results The number of days of inpatient observation was (12 ± 8.6) d in each observation group and (2.45 ± 1.05) times in hospital. The case fatality rate was 8%. The control group was (18 ± 7.7) d, (3 ± 1.26) times and the case fatality rate was 30%. There was significant difference between the two groups (P <0.01, 0.05 and <0.05, respectively). Conclusions Five-agent therapy based on antagonist has a significant effect on the treatment of CHF.