氟苯咪唑(Flubendazole),化学名:5-(4-氟苯甲酰基)-苯骈咪唑-2-氨基甲酸甲酯。它比同类化合物甲苯咪唑仅多一个氟取代基,两者具有相似的驱虫作用,对钩虫、蛔虫、蛲虫和鞭虫均有良好的驱虫效果,对丝虫也具有不同程度的杀灭能力。但甲苯咪唑在啮齿类动物实验中发现有致畸作用,而氟苯咪唑则未见有此作用乃为其特点之一;其作用机制可导致寄生虫消化道内皮细胞解体,使其蜕变、溶解以致死亡。但对宿主细胞结构毫无影响,对机体完全无害。 Flubendazole, chemical name: 5- (4-fluorobenzoyl) -benzimidazole-2-carbamate. It is more than the same compound mebendazole only one fluorine substituent, both have a similar deworming effect on hookworm, roundworm, pinworm and whipworm have a good deworming effect on filarial also have different degrees of killing ability. However, mebendazole has been found to have teratogenic effects in rodent experiments, and flubendazole has been found to be one of its hallmarks; its mechanism of action can cause disintegration of the parasite gastrointestinal endothelium causing it to degrade and dissolve death. But no effect on the host cell structure, completely harmless to the body.