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目的观察奥曲肽微量泵泵入联合垂体后叶素静脉滴注治疗肝硬化上消化道出血的临床效果。方法选择医院2014年2月-2016年3月肝硬化上消化道出血患者200例,给予奥曲肽联合垂体后叶素治疗,对比治疗前后的呕血黑便、血红蛋白减少、血压、脉搏等情况。结果治疗72 h后,患者呕血黑便率、血红蛋白极度减少率、舒张压>90 mm Hg率及脉搏>100次/min率均低于治疗前,差异均有统计学意义(P<0.05)。治疗72 h后,患者的临床症状大部分均有改善,总有效率为84.0%。结论奥曲肽微量泵泵入联合垂体后叶素静脉持续滴注治疗肝硬化上消化道出血,有利于促进患者的临床康复,且安全高效,值得临床深入应用。
Objective To observe the clinical effect of octreotide micropump pump and pituitrin intravenous infusion on cirrhosis with upper gastrointestinal bleeding. Methods Two hundred and seventy patients with cirrhosis and upper gastrointestinal bleeding were selected from February 2014 to March 2016 in our hospital. The patients were given octreotide combined with pituitrin to compare the hematemesis, hemoglobin, blood pressure and pulse before and after treatment. Results After 72 hours of treatment, the rates of hematemesis, extreme reduction of hemoglobin, diastolic blood pressure> 90 mm Hg and pulse rate> 100 beats per minute were all lower than those before treatment (P <0.05). After 72 hours of treatment, most of the patients had clinical symptoms improved, with a total effective rate of 84.0%. Conclusions Octreotide micropump pump combined with pituitrin continuous infusion in the treatment of cirrhosis and upper gastrointestinal bleeding is conducive to the promotion of clinical rehabilitation of patients and is safe and efficient, which is worth further clinical application.