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我院小兒科病人很多,对患气喘病人缺乏較好的剂型,因以氨茶硷(Aminophylline)的片剂或粉剂發給病人,在工作上和用量上都觉不便,因而我們採用了如下的抗哮喘合剂处方。氨茶硷 1.0克鹽酸麻黄素 0.1克枸櫞酸鉀 8.3克單糖漿(加果汁) 50毫升水加至100毫升但按照本处方配成的合剂二三日后即有沉淀析出,放置日期愈久則沉淀愈多,不再溶解,对使用上很觉不便。这种针狀結晶为氨茶硷中的茶硷(Theophy-lline)。根据文献[註1]記載,氨茶硷为混合物,含有茶硷 75～82%,乙二胺(Ethylendiamine) 12.3～13.8%,虽易溶于水,但放置即呈混濁,易吸收空气中二氧化碳而析出茶硷。因之我們認为沉淀析出的原因
Pediatric patients in our hospital a lot, the lack of a good form of asthma patients, because of the theophylline (Aminophylline) tablets or powder to the patient, both in the work and the amount of inconvenience, so we use the following anti- Asthma combination prescription. Aminophylline 1.0 g Ephedrine hydrochloride 0.1 g Potassium citrate 8.3 g Monosaccharide syrup 50 mg Water added to 100 ml But the mixture prepared according to this prescription precipitates after two or three days and the longer the storage date, More, no longer dissolved, very inconvenient to use. This acicular crystal is Theophylline in theophylline. According to the literature [1], aminophylline is a mixture containing 75-82% of theophylline and 12.3-13.8% of Ethylendiamine. Although soluble in water, it is turbid when placed, and can easily absorb carbon dioxide in the air And theophylline precipitation. Because of the reason we think of precipitation