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临床上证实乙型肝炎病毒(HBV)感染最简易的方法是血清HBV标记物(HBVM)的检测。目前临床多以血清免疫学HBVM作为诊断乙型肝炎的主要依据之一。然而临床及病毒学实验发现,血清乙型肝炎表面抗原(HBsAg)阴性并不能排除HBV感染,随着PCR方法对血清中HBV DNA检测及采用免疫组化法对肝
Clinically proven Hepatitis B virus (HBV) infection is the easiest way to detect serum HBV markers (HBVM). At present, clinical immunology HBVM as one of the main basis for the diagnosis of hepatitis B. However, clinical and virological experiments found that serum HBsAg negative and can not rule out HBV infection, with the PCR method for detection of serum HBV DNA and immunohistochemistry of the liver