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测定了92例急性心肌梗塞患者血超氧化物歧化酶(SOD),谷胱甘肽过氧化物酶(GSH-PX),丙二醛(MDA),发现AMI患者SOD,GSH-PX明显低于正常人,MDA明显高于正常人。这种变化的幅度因AMI的临床表现不同而异,AMI合并心衰,室速者MDA升高,SOD,GSH-PX降低最显著.提示上述指标与心肌缺血的严重程度有关.AMI患者脂质过氧化物及相关酶的测定对判断其预后有一定指导意义。
The serum levels of superoxide dismutase (SOD), glutathione peroxidase (GSH-PX) and malondialdehyde (MDA) were measured in 92 patients with acute myocardial infarction. The SOD and GSH-PX levels in AMI patients were significantly lower than Normal, MDA was significantly higher than normal. The magnitude of this change varies according to the clinical manifestations of AMI. AMI combined with heart failure, ventricular tachycardia increased MDA, SOD, GSH-PX decreased the most significant. Suggesting that the above indicators and the severity of myocardial ischemia. AMI patients with lipid peroxidation and related enzymes determination to determine the prognosis of a certain significance.