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为了针对同一病理肿瘤不同个体术后选择性应用最为敏感的化疗药物.我们对1992年1月~1996年12月收治的36例膀胱移行细胞癌患者术中取出的活体标本制成单细胞悬液,对其行化疗药物敏感性检测。结果显示:同一病理级别膀胱癌对各种抗癌药物敏感性不同;单药总体敏感率与病理分级明显相关,二药联合应用随分级增加其敏感性明显高于单药。根据药敏结果进行治疗,37例病人一年复发仅3例。体外药敏实验结果能指导临床用药,而且疗效较满意。
In order to target the same pathological tumor in different individuals after the selective application of the most sensitive chemotherapy drugs. We performed single-cell suspensions on live specimens taken from 36 patients with transitional cell carcinoma of the bladder treated from January 1992 to December 1996. Sensitivity tests were performed on chemotherapy drugs. The results showed that: the same pathological grade bladder cancer sensitivity to various anti-cancer drugs; single drug overall sensitivity rate and pathological grade was significantly related to the two drugs combined with the increase in the sensitivity of the classification was significantly higher than the single drug. According to drug susceptibility results, 37 patients relapsed only 3 cases a year. In vitro drug susceptibility test results can guide the clinical use of drugs, and the efficacy is satisfactory.