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目的:探讨血浆D-二聚体(D-D)水平与急性脑梗死的相关性。方法:用挪威耐科明公司生产的N ycoC ardR eaderⅡ多功能全定量金标检测仪以固相免疫双抗体夹心法对急性脑梗死组(观察组)和对照组各40例进行血浆D-D测定。结果:观察组D-D水平与对照组相比明显增高(P<0.01);观察组D-D水平与梗死体积、病程演变呈显著正相关(P<0.01)。结论:血浆D-D水平可作为判断急性脑梗死体积大小、病程演变的一种客观指标。
Objective: To investigate the relationship between plasma D-dimer (D-D) level and acute cerebral infarction. Methods: Plasma D-D was measured in 40 acute cerebral infarction patients (control group) and 40 control subjects by solid-phase immunofluorescence double-antibody sandwich method using the NcocoC ardR eader Ⅱ Multifunctional Quantitative Gold Label Detector manufactured by Norwich Pharma. Results: The D-D level in the observation group was significantly higher than that in the control group (P <0.01). The D-D level in the observation group was positively correlated with the infarction volume and the course of the disease (P <0.01). Conclusion: Plasma D-D level can be used as an objective index to judge the volume of acute cerebral infarction and the course of disease.