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目的:本文旨在探讨纳洛酮治疗肺性脑病的临床疗效。方法:对照组35例给予基础治疗。治疗组37例加用纳洛酮注射剂(0.8~1.2 m g加入0.9%氯化钠注射液46 m l中)持续静脉泵入,每8 h 1次。结果:治疗组总有效率显著高于对照组(P<0.05)。动脉血气分析指标氧分压(PaO2)显著高于对照组(P<0.05),动脉血二氧化碳分压(PaCO2)显著低于对照组(P<0.05)治疗过程中无不良反应发生。结论:纳洛酮治疗肺性脑病疗效确切、安全。
Objective: This article aims to investigate the clinical efficacy of naloxone in the treatment of pulmonary encephalopathy. Methods: 35 cases in the control group were given basic treatment. In the treatment group, 37 cases were given continuous intravenous injection of naloxone injection (0.8 ~ 1.2 m g, 0.9% sodium chloride injection 46 ml) once every 8 hours. Results: The total effective rate in the treatment group was significantly higher than that in the control group (P <0.05). The arterial blood gas analysis index PaO2 was significantly higher than that of the control group (P <0.05), and PaCO2 of arterial blood gas was significantly lower than that of the control group (P <0.05). No adverse reactions occurred during the treatment. Conclusion: Naloxone is effective and safe in the treatment of pulmonary encephalopathy.