论文部分内容阅读
目的了解输血所致 HBV 和 HCV 感染现状及 HBsAg、抗 HCV 和 ALT 筛检供血的效果.方法对138例输血者输血前、后1、3、6、9个月血清标本及其供血检测 HBsAg、抗 HBs、抗 HBc、抗 HCV 和 ALT,并对部分血清标本用 PCR及巢式 RT-PCR 法检测 HBV DNA 和 HCV RNA.结果和结论输血后 HBV 和 HCV 感染率分别为1.4%(2/138)和34.8%(48/138),输血后乙型和丙型肝炎发生率分别为0.7%(1/138)和14.5%(20/138),21例(15.2%)输血后肝炎中,输血后丙型肝炎占95.2%,输血所致 HCV 感染已成为输血后肝炎的主要原因.抗 HCV 阳性和/或 ALT 升高的供血与输血后HCV 感染密切相关,HBsAg、抗 HCV 和 ALT 筛检供血是目前较有效防止输血后 HBV 和 HCV 感染的方法。
Objective To investigate the status of HBV and HCV infection caused by blood transfusion and the effect of HBsAg, anti-HCV and ALT screening blood supply.Methods The blood samples of 138 transfused persons before, 1, 3, 6 and 9 months after blood transfusion were tested for HBsAg, Anti-HBs, anti-HBc, anti-HCV and ALT, and some serum samples were detected by PCR and nested RT-PCR for HBV DNA and HCV RNA.Results and Conclusion The HBV and HCV infection rates after transfusion were 1.4% (2/138 ) And 34.8% (48/138) respectively. The incidences of hepatitis B and C after transfusion were 0.7% (1/138) and 14.5% (20/138) respectively in blood transfusions, and in 21 cases (15.2% Hepatitis C infection accounted for 95.2%, and HCV infection caused by blood transfusion has become the main cause of post-transfusion hepatitis.Healthy and / or elevated ALT blood supply is closely related to HCV infection after blood transfusion, HBsAg, anti-HCV and ALT screening blood supply It is the most effective method to prevent HBV and HCV infection after transfusion.