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骨巨细胞瘤罕见,且症状与自然病程多变,因其局部的侵袭性或因治疗而致显著的功能后遗症。作者回顾分析1959～1991年21例局限性骨巨细胞瘤放疗的结果,重点评价兆伏放疗的效果、副反应及确定放疗的指证。女14例,男7例,平均32岁(13～71)。原发癌部位四肢9例,盆骨6例,脊椎4例,颅骨2例。18例有骨外侵犯,且14例扩展到邻近结构(包括脊髓压迫3例,马尾压迫1例,骶丛侵犯3例,颞叶侵犯1例)。颅骨侵犯的2例除颞骨1例侵犯脑实质外,另1例上颌窦
Giant cell tumors of the bone are rare, and symptoms and natural course vary, due to their local invasiveness or significant functional sequelae due to treatment. The authors retrospectively analyzed the results of radiotherapy for 21 cases of localized giant cell tumor of bone from 1959 to 1991, and focused on evaluating the efficacy, side effects and indications of radiotherapy for megavoltage radiation therapy. There were 14 females and 7 males, with an average age of 32 (13-71). The primary site of cancer was 9 cases of limbs, 6 cases of pelvis, 4 cases of vertebrae, and 2 cases of skull. 18 cases had extraosseous invasion, and 14 cases extended to adjacent structures (including 3 cases of spinal cord compression, 1 case of horsetail compression, 3 cases of sacral plexus invasion, and 1 case of temporal lobe invasion). 2 cases of skull invasion except 1 case of humerus invaded the brain parenchyma, another case of maxillary sinus