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阻塞性睡眠呼吸暂停可引起血液动力学负荷和肾上腺素能负荷而诱发心力衰竭。本文研究旨在验证心功能衰竭患者可用持续气道正压治疗阻塞件睡眠呼吸暂停,从而改善左室收缩功能。 方法 24例左室射血分数≤45％并伴发阻塞性睡眠呼吸暂停患者接受心功能衰竭最佳药物治疗,做了睡眠状态描记,并在翌晨用体积描记数码照相法测量血压和心率,用超声心动描记评估左室大小和左室射血分数,然后将患者随机分为单独接受药物治疗组(对照组,12
Obstructive sleep apnea can cause hemodynamic load and adrenergic load induced heart failure. The purpose of this study was to verify that patients with heart failure can be treated with continuous positive airway pressure in obstructive sleep apnea to improve left ventricular systolic function. Methods Twenty-four patients with left ventricular ejection fraction ≤ 45% and patients with obstructive sleep apnea were treated with the best medication for heart failure and their sleep state was recorded. Blood pressure and heart rate were measured by plethysmographic digital photography method the next morning, Left ventricular ejection fraction and left ventricular ejection fraction were assessed by echocardiography and then patients were randomly assigned to receive either drug alone (control group, 12