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目的探讨新会区妊娠梅毒的发生情况,妊娠不同时期、不同疗程治疗对妊娠结局的影响。方法回顾性分析新会区各助产机构分娩的61例妊娠梅毒产妇的临床资料。结果孕28周前治疗新生儿梅毒滴度低于母亲的比率高于孕28周后,且早产、低体重儿发生率均明显低于孕28周后(P<0.05);治疗2个疗程较1个疗程产妇所生新生儿梅毒滴度低于母亲的比率(P<0.05);53例接受治疗的妊娠梅毒产妇均无发生死胎和先天梅毒;8例无治疗的产妇死胎2例、先天梅毒1例。结论对妊娠梅毒及早筛查及早诊断,早期足疗程规范治疗可以有效降低不良妊娠结局和先天梅毒的发生。
Objective To investigate the incidence of syphilis during pregnancy in Xinhui District and the effect of different courses of treatment on pregnancy outcomes at different stages of pregnancy. Methods The clinical data of 61 pregnant women with syphilis who were delivered by various midwifery institutions in Xinhui district were analyzed retrospectively. Results The rate of syphilis titers in neonates was lower than that of mothers 28 weeks after gestation. The incidence of preterm birth and low birth weight babies was significantly lower than that of pregnant babies after 28 weeks (P <0.05). The two courses of treatment Neonatal syphilis titers were lower than that of mothers in one course of treatment (P <0.05) .There was no stillbirth and congenital syphilis in 53 pregnant women with gestational syphilis, 8 untreated maternal stillbirths, congenital syphilis 1 case. Conclusion Early detection of syphilis in pregnancy and early diagnosis of early foot treatment regimen can effectively reduce adverse pregnancy outcomes and congenital syphilis.