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一项最新研究结果显示,血管紧张素转换酶抑制剂(ACEI)与钙通道阻滞剂(CCBs)联合治疗对降低左心室质量的效果要好于大剂量单一药物治疗。因为 ACE 抑制剂与 CCBs 可通过不同机制发挥作用,研究人员由此推测,联合应用两类药物可能要比单一大剂量应用该类药物对动脉更有利。为了评价这一问题,来自于美国加利福尼亚州奥兰治郡心脏学会和研究中心的 Joel M.Neutel 博士及其同事对106例年满18岁或18岁以上的患者开展了一项前瞻性的随机开放性研究。所有患者均患
A new study shows that the combination of angiotensin converting enzyme inhibitor (ACEI) and calcium channel blockers (CCBs) is more effective in reducing left ventricular mass than high-dose single-agent therapy. Because ACE inhibitors and CCBs work through different mechanisms, the researchers hypothesized that the combination of both drugs might be more beneficial to the arteries than the single bolus of the drug. To assess this issue, Dr. Joel M. Neutel from the Heart County Cancer Institute and Research Center in Orange County, California, USA, and colleagues conducted a prospective randomized trial of 106 patients 18 years of age or older Sexual research. All patients are affected