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目的探讨血浆脑钠肽(BNP)水平在慢性肺源性心脏病患者中的临床价值。方法选取2014年4月-2015年4月住院治疗的110例慢性肺源性心脏病患者作为实验组,分别测定入院治疗前和治疗后的血浆BNP、PaCO_2、PaO_2水平;另选取同期体检的健康者110例作为对照组,分别测定其与实验组相同的检查项目,对两组研究对象的测定结果进行比较分析。结果实验组通过治疗后,在缓解期血浆BNP水平明显低于治疗前,差异具有统计学意义(P<0.05);实验组治疗前血浆BNP水平明显高于对照组,差异具有统计学意义(P<0.05)。结论血浆脑钠肽水平是肺源性心脏病诊断和预后的可靠指标之一,具有一定的临床价值。
Objective To investigate the clinical value of plasma brain natriuretic peptide (BNP) levels in patients with chronic cor pulmonale. Methods A total of 110 patients with chronic cor pulmonale who were hospitalized from April 2014 to April 2015 were selected as the experimental group, and plasma BNP, PaCO_2 and PaO_2 levels were measured before and after admission. The health status of the patients 110 cases as control group, respectively, the same test items were measured with the experimental group, the results of the two groups of subjects were analyzed comparative analysis. Results After treatment, the level of plasma BNP in remission group was significantly lower than that before treatment (P <0.05). The BNP level in experimental group before treatment was significantly higher than that in control group (P <0.05). Conclusions The level of plasma brain natriuretic peptide is one of the reliable indicators for the diagnosis and prognosis of pulmonary heart disease and has certain clinical value.