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目的了解不同时期淄博市城区儿童肺功能的变化情况。方法基于1992年历史资料,选择区域相近的污染区和对照区,于2013年10月开展儿童肺功能检查,对比分析不同时期儿童肺功能指标的变化情况。结果同时期儿童肺功能指标(VC、FVC、FEV1、MMEF、PEF、FEF75%、FEF50%、FEF25%)比较,1992年对照区为(2.06±0.29)L、(1.98±0.35)L、(1.79±0.28)L、(2.02±0.41)L/s、(3.43±0.81)L/s、(3.06±0.62)L/s、(1.92±0.47)L/s、(0.94±0.28)L/s,分别高于污染区(1.75±0.24)L、(1.73±0.22)L、(1.57±0.25)L、(1.75±0.35)L/s、(2.91±0.58)L/s、(2.56±0.55)L/s、(1.68±0.47)L/s和(0.85±0.22)L/s,差异均有统计学意义(P<0.05),2013年对照区为(2.23±0.46)L、(2.16±0.46)L、(2.11±0.39)L、(2.55±0.73)L/s、(4.30±0.90)L/s、(3.98±0.87)L/s、(2.85±0.81)L/s、(1.53±0.56)L/s,污染区为(2.31±0.51)L、(2.28±0.51)L、(2.07±0.1)L、(2.48±0.61)L/s、(4.10±0.97)L/s、(3.84±0.86)L/s、(2.82±0.68)L/s、(1.45±0.45)L/s,差异无统计学意义(P>0.05);不同时期比较,2013年污染区儿童肺功能指标均高于1992年污染区(P<0.05),2013年对照区(FEV1、MMEF、PEF、FEF75%、FEF50%、FEF25%)均高于1992年对照区(P<0.05);年龄趋势分析表明,1992年和2013年污染区、对照区儿童FEV1均有随着年龄增加而升高的趋势,1992年对照区各年龄组FEV1明显高于污染区。结论淄博市城区2013年儿童肺功能各指标相比1992年有明显改善。
Objective To understand the changes of lung function in children in Zibo City in different periods. Methods Based on the historical data of 1992, we selected the polluted areas and the control areas with similar areas. In October 2013, the pulmonary function tests were performed to compare and analyze the changes of pulmonary function indexes in children at different periods. Results Compared with the control group (1992), the control group (2.06 ± 0.29) L, (1.98 ± 0.35) L, (1.79 ± 0.28) L / s, (2.02 ± 0.41) L / s, (3.43 ± 0.81) L / s, (3.06 ± 0.62) L / s, (1.92 ± 0.47) L / s, (1.75 ± 0.35) L / (2.91 ± 0.58) L / s and (2.56 ± 0.55) L were significantly higher than those in the contaminated area (1.75 ± 0.24) L, (1.68 ± 0.47) L / s and (0.85 ± 0.22) L / s, respectively, with statistical significance (P <0.05) (2.11 ± 0.39) L, (2.55 ± 0.73) L / s, (4.30 ± 0.90) L / s, (3.98 ± 0.87) L / s, (2.85 ± 0.81) L / s and (1.53 ± 0.56) (2.31 ± 0.51) L, (2.07 ± 0.1) L, (2.48 ± 0.61) L / s, (4.10 ± 0.97) L / s, and (3.84 ± 0.86) L / (2.82 ± 0.68) L / s, (1.45 ± 0.45) L / s respectively, with no significant difference (P> 0.05). Compared with different periods, the indexes of lung function in children in the contaminated area in 2013 were all higher than those in 1992 (P <0.05). The control area (FEV1, MMEF, PEF, FEF75%, FEF50% and FEF25%) in 2013 was higher than that in 1992 (P <0.05) And trends in 2013 contaminated area, control area children have FEV1 increased with increasing age, in 1992, the control area in each age group FEV1 was significantly higher than the contaminated area. Conclusion The indexes of lung function in children in Zibo city in 2013 have obviously improved compared with those in 1992.